Epidemija koronavirusa (Covid-19 / SARS-Cov2) - dnevne aktuelnosti iz zemlje i sveta

[Wookie]

Astrazeneka prva i druga doza, pa Fajzer treća, ali nisam primetio da se nešto pogoršalo zujanje nakon vakcina. Mada, ima puno mogućih uzroka za tinitus, tako da ko zna, možda i vakcina može da utiče.

[wwww]

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The Paul Ehrlich Institute (PEI) reports on 172,188 suspected cases of side effects or vaccination complications reported from Germany in the temporal connection with the vaccination with the mRNA vaccines Comirnaty (BioNTech Manufacturing GmbH) and Spikevax (MODERNA BIOTECH SPAIN, SL) as well as the vector vaccines Vaxzevria (AstraZeneca AB) and COVID-19 Vaccine Janssen to protect against COVID-19 from the start of the vaccination campaign on December 27th, 2020 to September 30th, 2021.

 

According to the Robert Koch Institute, 107,888,714 vaccinations were carried out by September 30, 2021, of which

82,341,579 vaccinations with Comirnaty (Pfizer-BioNTech)

9,668,138 vaccinations with Spikevax (MODERNA)

12,692,700 vaccinations with Vaxzevria (AstraZeneca) and

3,186,297 vaccinations with COVID-19 Vaccine Janssen.

 

94,281 suspected cases of vaccination with Comirnaty (PB) were reported,

25,713 suspected cases of Spikevax (Moderna),

45,178 suspected cases of Vaxzevria (AstraZeneca) and

6,243 reports of COVID-19 Vaccine Janssen.

 

In 773 reported suspected cases, the COVID-19 vaccine was unspecified.

 

The reporting rate for all vaccines together was 1.6 reports per 1,000 vaccine doses, for serious reactions 0.2 reports per 1,000 vaccine doses.

izvestaj na nemackom:

https://www.pei.de/SharedDocs/Downloads/DE/newsroom/dossiers/sicherheitsberichte/sicherheitsbericht-27-12-20-bis-30-09-21.pdf?__blob=publicationFile&v=8

 

nabrojali su ove moguce nezeljene efekte:

- Myokarditis i Perikarditis - kod mladjih muskaraca, pojavljuje se nekoliko dana posle druge doze mRNA vakcine, uz odredjenu terapiju se ovo resava; prijavljeno 1243 sumnjiva slucaja, pri cemu je veci rizik kod Moderne; slicno je uocceno u Kanadi, Danskoj, Finskoj, Norveskoj i Svedskoj; FDA nije nasla razliku u efektu PB i Moderne.

- Anaphylaxie - veoma retka reakcija na sve 4 vakcine (6 slucajeva na milion prvih doza za mRNA vakcine, 1-2 slucaja na milion drugih doza, slicno i za AZ, dok je za JJ nesto manje: 2 slucaja na milion doza)

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According to the prescribing information for both mRNA vaccines and Vaxzevria, people who develop an anaphylactic reaction after the first dose should not be given a second dose. The results of retrospective studies indicate, however, that people with immediate allergic reactions including symptoms that suggest an anaphylactic reaction could safely be re-vaccinated after a proper allergological diagnosis, since the patients mostly do not have a real (immunoglobulin E-mediated) allergic one Showed immediate reaction.

 

- Thrombose s Thrombozytopenie-Syndrom (TTS) - lokalizovano (cerebralne vene, slezene, jetra ili mezenterične vene), kod AZ i JJ vakcina (neke i s smrtnim ishodom), mnogo redje se javlja posle 2. doze AZ;

- Guillain-Barré-Syndrom - kod AZ i JJ, 1 slucaj na 100.000/120.000 doza.

- Thrombozytopenie i Immunthrombozytopenie (ITP) - kad imuni sistem napada krvne plocice (koje su potrebne za normalno zgrusavanje krvi). Prijavljeno kod AZ i JJ (do 4 sedmice od vakcinacije), nisu kod mRNA vakcina; oni koji su imali prethodno problema s ovim trebalo bi da obrate paznju (ja bih rekla: da izbegnu AZ i JJ i uzmu mRNA vakcinu).

- Thrombose  - bilo vise studija koje su ispitivale PB i AZ u vezi ovog ali nisu imali neki poseban zakljucak sto se tice povecanog rizika (mnogo veci rizik je pri infekciji).

 

 

vakcina - prijavljeni sumnjivi slucajevi (na 1000 vakcina) - tezi slucajevi (na 1000 vakcina):

PB -           94.281 (1,1) - 12.939 ili 13,7% (0,16)

Moderna - 25.713 (2,7) -  1.493 ili 5,8% (0,15)

AZ -           45.178 (3,6) -  5.751 ili 12,7% (0,45)

JJ -             6.243 (2,0) -     560 ili 9,0% (0,18)

nepoznato -   773          -    311

ukupno:     172.188 (1,6) - 21.054 ili 12,2% (0,2)

 

u izvestaju su dati i neki dijagrami gde su preracunali % za pojedine vakcine,

 

kao i ucestalost nezeljenih efekata (bol na mestu uboda, glavobolja, umor, temperatura, vrtoglavica, simptomi gripa, jeza, mucnina, osip, povracanje itd.)

 

Ima i tabela i dijagram za ucestalost Myo-/Perikarditisa po starosnim grupama za PB i Modernu, plus "ishod":

12% se vratilo na staro

12% poboljsalo se stanje

55% jos se nije vratilo na staro do trenutka pisanja izvestaja

2% ostala ostecenja

1% preminuli

18% nepoznato

 

za Thrombose s Thrombozytopenie su za AZ imali 189 slucajeva:

- 109 zena ili 1,78 na 100.000 doza (14 umrlih) i

- 79 muskaraca ili 1,20 na 100.000 doza (11 umrlih).

5 slucajeva su posle 2. doze AZ.

Najvecu ucestalost su imali kod zena od 40-49 godina (3,87 slicajeva na 100.00 doza), a kod muskaraca od 30-39 godina (3,86 slicajeva na 100.00 doza).

 

Kod JJ su imali 20 slucajeva:

- 5 zena ili 0,45 na 100.000 doza (2 umrle) i

- 14 muskaraca ili 0,67 na 100.000 doza (2 umrla),

za jednu osobu nisu imali podatak o polu.

 

Kod PB su imali 33 slucaja:

- 17 zena ili 0,04 na 100.000 doza (4 umrle) i

- 16 muskaraca ili 0,04 na 100.000 doza (1 umro)

 

Kod Moderne su imali 5 slucajeva:

- 4 zene ili 0,08 na 100.000 doza (0 umrle) i

- 1 muskaraca ili 0,02 na 100.000 doza

 

itd.

[Pletilja]

9 hours ago, Wookie said:

Ja imam tinitus godinama, ni ne sećam se kad je to počelo, ali nisam primetio da se nešto pojačalo nakon vakcine, jednako zuji ko i uvek.

Isto....ne zuji nego vise onako - ssssssssssss.............skoro nestalo tokom "virusne infekcije srednjeg uha" (ordinirajuci specijalista) dok sam pila Urutal, doslo mi je da ga pijem do kraja zivota jer je mnogo lepo kad ti nista ne ssssssssssssssss u glavi ali ne moze....😄

[Clash]

12 hours ago, Tomiprunet said:

 Na koronu sam otporan, ne perem ruke cesto, nosim jednu masku kn95 evo vec godinu dana, pre nje sam nosio obicnu hirursku isto godinu dana ali sam zamenuo za ovu crnu kn95 jer se obicna hirurska brzo prlja. Ova je crna, ne vidi se. 

Em prakticno (srpska škola), em elegantno (francuska škola). 

Slaviša šampion.

[urosg3]

12 hours ago, Tomiprunet said:

Od lekova nista ne koristim, jedino aspirin ako mi se javi bol u ledjima. i ove suplemente za bolji vid. to je to. Na koronu sam otporan, ne perem ruke cesto, nosim jednu masku kn95 evo vec godinu dana, pre nje sam nosio obicnu hirursku isto godinu dana ali sam zamenuo za ovu crnu kn95 jer se obicna hirurska brzo prlja. Ova je crna, ne vidi se. Grip nikad nisam imao, niti sam primio ikad vakcinu. Za koronu sam primio dve doze.

Za bold burazeru samo Fajzer i k`o rukom odneseno 😉
 

[fancy]

7 hours ago, wwww said:

Kod PB su imali 33 slucaja:

- 17 zena ili 0,04 na 100.000 doza (4 umrle) i

- 16 muskaraca ili 0,04 na 100.000 doza (1 umro)

 

Pfizer, satire.

Since 1998.

[duško matić]

Meni se javi zujanje u ušima kad imam povišen pritisak, što je česta pojava a u poslednje vreme mi se javlja i kad pušim travu 😄

Prijavio sam se preko poruke za modernu kao buster posle dva fajzera, ne znam da li je uopšte imaju u NS, ako mi ne stigne poziv u narednih par dana, poslaću novu prijavu ali za fajzera.

[Tomiprunet]

39 minutes ago, urosg3 said:

Za bold burazeru samo Fajzer i k`o rukom odneseno 😉
 

Primio sam dva puta.

1 hour ago, Clash said:

Em prakticno (srpska škola), em elegantno (francuska škola). 

Slaviša šampion.

Najbolje od oba sam ukrstio.

[urosg3]

1 minute ago, Tomiprunet said:

Primio sam dva puta.

 

izgleda da radi tek nakon 3. doze 3x bog pomaže 🙂

[erwin]

 

[Brian Setzer]

11 hours ago, Laki21 said:

Milanović je psihopata Vučićevskog tipa.

 

Ima on dovoljno materijala za posebnu temu. Što se tiče vakcinacije i mera, koliko znam, vakcinisao se i trećom dozom.

[erwin]

  

Quote

Nasal COVID vaccine causes minimum side effects — developer

According to deputy director of the Gamaleya National Research Center of Epidemiology and Microbiology Denis Logunov, its use will make it possible to ensure extra protection in the upper respiratory airways

MOSCOW, November 21. /TASS/. A nasal form of the coronavirus vaccine causes minimum side effects and its use will make it possible to ensure extra protection in the upper respiratory airways, deputy director of the Gamaleya National Research Center of Epidemiology and Microbiology, Denis Logunov, said on Sunday.

"It [the use of a nasal vaccine] is convenient for vaccination. It is painless, with an absolute minimum of side effects. Moreover, it will make possible to achieve the main goal: to develop systemic immunity after the primary vaccination and to create an additional barrier in the upper respiratory airways after the additional intranasal immunization," he said at a meeting with Russian President Vladimir Putin.

According to Logunov, the use of the nasal vaccine will begin shortly after the clinical tests.

In October, the Gamaleya Center received a Russian health ministry’s permit for the second phase of clinical tests of a nasal form of the coronavirus vaccine. The Center’s director Alexander Gintsburg said that the nasal form would be an addition to the regular vaccine to ensure an extra barrier to the infection.

https://tass.com/society/1364365

[JPM]

12 hours ago, mmajstor said:

Svakako ne treba slepo povezivati dva dogadjaja koja ne moraju obavezno da budu uzrocno posledicno vezana samo ako se vremenski podudaraju.

 

Znas kako se kaze, svi cemo umreti nakon vakcine.

 

Neko za dva dana, neko za 80 godina.

[erwin]

Po podacima SZO od sredine septembra čak 8 sprej-vakcina protiv kovida je u kliničkim testiranjima.
 

Quote

Vaccine nasal sprays aim to 'shut door' on virus

Could delivering COVID-19 immunity directly to the nose -- the area of the body via which it is most likely to be transmitted -- help conquer the pandemic? 

The World Health Organization says clinical trials are underway to evaluate eight nasal spray vaccines that target COVID-19.  

The most advanced effort so far by China's Xiamen University, the University of Hong Kong and Beijing Wantai Biological Pharmacy has completed phase-2 trials.

"When the virus infects someone it usually gets in through the nose," said researcher Nathalie Mielcarek who is working with the Lille Pasteur Institute to develop a nasal spray vaccine against whooping cough. 

"The idea is to shut the door."

An article published in Scientific American in March urged developing nasal spray vaccines because they have an immediate effect on the virus in an infected person's mucus. 

There they trigger production of an antibody known as immunoglobulin A, which can block infection. 

"This overwhelming response, called sterilising immunity, reduces the chance that people will pass on the virus," said the article. 

The vaccines currently available offer strong protection against severe forms of COVID-19 but are less reliable at preventing the spread of the virus. 

Stimulating immunity directly in the nose "lowers the risk of infecting other people", said Mielcarek.

"From there you have less of the virus infecting the lungs and so fewer severe cases since the viral load is lower," she added.

An article published in March by Gavi the Vaccine Alliance noted other advantages, including the fact that the sprays don't need refrigeration and don't need to be administered by health professionals.

"People would be able to self-administer them at home," the article says, adding "they are likely to be more popular for the millions of people who don’t like needles".

And in a French study on mice presented last week, 100 percent of subjects vaccinated with the spray survived infection by Covid-19 while all unvaccinated mice died. 

"The vaccinated animals... showed low levels of the virus so they are not contagious anymore -- that's one of the advantages of the nasal spray," Philippe Mauguin, CEO of the French institute that hopes to patent the vaccine told AFP. 

Isabelle Dimier-Poisson who led the research has high hopes.

"It could allow us to get back to life before the pandemic, without social distancing, and without masks," she said.

https://www.philstar.com/lifestyle/health-and-family/2021/09/18/2128050/vaccine-nasal-sprays-aim-shut-door-virus
 

 

Edited November 23, 2021 by erwin

[DJ_Vasa]

2 minutes ago, erwin said:

Po podacima SZO od sredine septembra čak 8 sprej-vakcina protiv kovida je u kliničkim testiranjima.

 

 

Jesu li se oglasili avaksi po pitanju čipova u spreju?

[urosg3]

Na Jutarnjem sam natrčao na zanimljiv tekst, na dosta mesta pogađa ono što mislim mada se razilazimo po pitanju obavezne vakcinacije.

[Clash]

7 minutes ago, urosg3 said:

Na Jutarnjem sam natrčao na zanimljiv tekst, na dosta mesta pogađa ono što mislim mada se razilazimo po pitanju obavezne vakcinacije.

Pa da, slazes se sa tipom koji mora na radnom mestu da nosi periku.

[urosg3]

Just now, Clash said:

Pa da, slazes se sa tipom koji mora na radnom mestu da nosi periku.

🙂 ma to i nekako ali valjda ne nosi masku i periku istovremeno to bi bilo urnebesno

[Sunshine State]

Pogubih se s pravilima 😞

 

Pomagajte - druga doza Pfizera dobijena pre 7 meseci - da li ce mi QR kod u Srbiji pokazivati "nekompletnu vakcinaciju"?

 

Jos jedna pomoc potrebna - drugar dolazi iz US za Srbiju u petak, vakcinisan s dve doze Pfizera (druga doza pre 7 meseci); Ameri nemaju QR kodove, imaju kartoncice s upisanim podacima o datim Covid vakcinama - kako se te "Covid propusnice" tretiraju u Srbiji, da li se, uopste, prihvataju?

 

Hvala!

[duško matić]

22 minutes ago, Sunshine State said:

Pomagajte - druga doza Pfizera dobijena pre 7 meseci - da li ce mi QR kod u Srbiji pokazivati "nekompletnu vakcinaciju"?

Kad se skenira biće crveno, kao da nisi imunizovana, ako prodje 7 meseci.

[Cyber]

16 minutes ago, Sunshine State said:

Pogubih se s pravilima 😞

 

Pomagajte - druga doza Pfizera dobijena pre 7 meseci - da li ce mi QR kod u Srbiji pokazivati "nekompletnu vakcinaciju"?

 

Jos jedna pomoc potrebna - drugar dolazi iz US za Srbiju u petak, vakcinisan s dve doze Pfizera (druga doza pre 7 meseci); Ameri nemaju QR kodove, imaju kartoncice s upisanim podacima o datim Covid vakcinama - kako se te "Covid propusnice" tretiraju u Srbiji, da li se, uopste, prihvataju?

 

Hvala!

 

Aktuelne informacije o tim stvarime se uvek nalaze na sajtovima ministarstva inostranih poslova. Za ulazak u Srbiju ovde. 

[urosg3]

Opa: 

Prijavljen novi soj kovida: Brzo se širi, nema simptoma; SZO: Pratimo

[Clash]

32 minutes ago, Sunshine State said:

Pogubih se s pravilima 😞

 

Pomagajte - druga doza Pfizera dobijena pre 7 meseci - da li ce mi QR kod u Srbiji pokazivati "nekompletnu vakcinaciju"?

 

 

Hvala!

 

9 minutes ago, dulematic said:

Kad se skenira biće crveno, kao da nisi imunizovana, ako prodje 7 meseci.

Mozes sama skenirati svoj kod, ne treba ti qr scaner, dovoljna ti je kamera telefona i salje te na e upravu.

[Sunshine State]

8 minutes ago, Cyber said:

 

Aktuelne informacije o tim stvarime se uvek nalaze na sajtovima ministarstva inostranih poslova. Za ulazak u Srbiju ovde. 

 

To sam vec pogledala, jasno je sta  treba za ulazak u Srbiju, to nije bilo moje pitanje

 

Ono sto ne pise tu je ono sto ja pitam - o vaznosti sertifikata nakon vise od 6 meseci od druge doze, o tome  kako se "serifikati" (US kartoncici) tretiraju u Srbiji...

 

 

[erwin]

11 minutes ago, urosg3 said:

Opa: 

Prijavljen novi soj kovida: Brzo se širi, nema simptoma; SZO: Pratimo

 

Ne treba se previše oslanjati na ono što srpski "mediji" objave. Apsolutno nije tačno da nema simptoma, istina je da je manje ljudi simptomatično i da manje ljudi ima klasične simptome kovida, poput kašlja i temperature.

 

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Thursday’s findings also showed that the AY.4.2. mutation was less likely to cause symptomatic infection than other strains of the virus.

Two-thirds of people with AY.4.2. reported “any symptom,” compared to more than 75% of those with the U.K.’s dominant AY.4 strain.

Just a third of those infected with the AY.4.2. subvariant had “classic Covid-19 symptoms” — such as a cough or a temperature — compared to almost half of the people with AY.4.

https://www.cnbc.com/2021/11/18/delta-covid-mutation-is-on-the-rise-in-the-uk-study.html

Edited November 23, 2021 by erwin