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U poslednjih 24h u Nemackoj inficirano 1510 (najvise od kraja aprila). 39% inficiranih prosle sedmice su bili povratnici iz inostranstva (moze da ima veze s tim sto se oni obavezno testiraju pa se tu hvataju i asimptomaticni, za razliku od onih inficiranih u samoj Nemackoj). % "uvezenih" infekcija po sedmicama poslednja 2 meseca: 26. sedmica (22.-28.6.) - 3% 27. - 7% 28. - 11% 29. - 12% 30. (20.-26.7.) - 13% - ovde negde je uvedeno besplatno dobrovoljno testiranje povratnika 31. - 21% 32. - 34% - ovde negde je uvedeno obavezno testiranje povratnika iz kriticnih oblasti 33. - 39% u poslednje 4 sedmice inficirani - po zemljama u kojima su se inficirali: Nemacka+ostali - 62,4% Kosovo - 11,5% Turska - 7.4%Lagebericht - 2020-08-18-de.pdf Hrvatska - 5,15% Bugarska - 2,1% BiH - 1,95% Spanija - 1,46% Srbija - 1,38% Rumunija - 1,26% Poljska - 1,07% Makedonija -1,06% Albanija - 1% Austrija - 0,66% Francuska - 0,59% Italija - 0,52% Malta - 0,47% U poslednjih 13 sedmica vise se inficira muskaraca nego zena (za koji procenat; prosle sedmice 53% muskaraca, 47% zena). Hospitalizacija je trenutno na 6% (poslednje 4 sedmice: 9%, 9%, 7% i 6%), broj preminulih je ispod 1%. Poslednjih sedmica raste udeo omladine u broju inficiranih (slika 9, strana 9: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Situationsberichte/2020-08-18-de.pdf?__blob=publicationFile ), posebno raste broj inficiranih u grupi 15-34 godina starih i 5-14 godina starih (slika 8, strana 8), zapravo najvise ovi od 20-29 i od 10-19 godina stari (slika 9). Matori se cuvaju.

2. That's 20-40% of people who get infected and never show symptoms. More likely in young. Who don't understand they are propagating the pandemic "Usually a virus that is good enough to kill you would make almost everybody at least a little bit sick." 3. The chronic "long covid" post-viral symptoms of #COVID19 are common, understudied to date. "And it's extraordinary how many people have a postviral syndrome that's very strikingly similar to myalgic encephalomyelitis/chronic fatigue syndrome." 4. We don't have a #COVID19 czar with decision-making authority, like @RonaldKlain for Ebola (who Fauci loves) but @VP has taken on a lead role, is receptive, and "deeply involved." Fauci is very respectful to the Administration despite all the efforts of @POTUS to undermine him 5. What about the @HHSgov hijacking the @CDCgov covid data? Fauci only learned about it by watching television 6. What about the hyperimmune response to #COVID19 and that being implicated as the basis for most fatalities? 7. It took 5 days from the sequence of #SARSCoV2 to Fauci's team to get the start on a vaccine, 62 days to get Phase 1 clinical trial started (That is simply incredible) 8. What about short-lived antibodies to the virus and the role of T cells? #SARSCoV2 is like SARS with a significant and enduring T cell response. We shouldn't be worried about the IgG antibody waning report that got a lot of buzz this week. 9. What about reinfection, does it occur? There are anecdotes, but no proof of replication competent virus. So if it really exists it's rare (considering millions of infections). Hard to prove since you need a BSL-3 lab to correlate PCR results of RNA nucleotides w/ live virus 10. On the mask pushback, Fauci attributes this to the "disturbing anti-science trend" My worry is that will extend to implementing the vaccine, but we didn't get to that issue 11. Monoclonal (neutralizing) antibodies were developed for Ebola and highly successful They are now in clinical trials for SARSCoV2, very potent, and will likely be used in early and late stages of treatment. Mabs don't get the attention of vaccines but very important & imminent 12. Rapid diagnostic kits for home or point of care are in the works, NIH has invested $500 million, results in < 30 mins. These will be transformative when they are available this fall 13. Favorite part: his comments to the frontline heroes and how science will prevail.

Ja sam shvatila da je kod vas veliki problem sto ste tokom leta u klimatizovanim prostorijama, a to moze da bude kriticno. Posebno ako vazduh samo cirkulise okolo ohladjen, a nema novog, friskog vazduha da se ubaci u sistem (plus nema adekvatnih filtera za ovu svrhu). I meni je delovalo logicnije da je za virus nezgodnije ako je vazduh suv, ali Australijanci nasli drugacije (a ovo sam cula vec vise puta u prethodnih nekoliko meseci)

A very interesting study from Australia shows again that dry air, not temperature, increases the risk of SarsCoV-2 transmission. 1% lower humidity, 7-8% more infections. Aerosols could be due to longer air retention times. The link between dry air and more infections could also be due to the virus itself. It follows from this that the risk in Germany is likely to increase in winter, especially indoors. But by humidifying the air, countermeasures might also be possible in classrooms.

Camping only with the Corona app - this applies from Tuesday at the Dyksterhus campsite in Krummhörn. The boss wants to prevent corona deniers from spreading the virus among the guests.

Austrijanci su imali i sami jedan hot spot gde su se ugostiteljski radnici - praktikanti (uglavnom omladina) pozarazavali u jednom mestu (Wolfgangsee) jer su partijali u slobodno vreme. Nije da su imuni na neodgovorno ponasanje. https://www.tagesschau.de/ausland/oesterreich-corona-wolfgangsee-101.html

Otkud ti to da Nemci optuzuju Hrvatsku za sirenje virusa? Mislim da sam dovoljno puta pisala sta se cuje na vestima gde su se ljudi zarazili: od partijanja omladine u delovima grada za izlazak (bilo da se radi o Kelnu, Dizeldorfu, Bohumu ili nekom drugom gadu), do svadbi i slicnih veselja i okupljanja, verskih obreda pa do partijanja po Majorci, Bugarskoj, pa do fabrika mesa, poljoprivrednih dobara gde rade sezonci. Mislim da sam stavljala i tabelu s podacima koliko novozarazenih je povezano s zemljama koje su proglasene za zarista (nekih 10% bilo kad sam poslednji put gledala, cini mi se), pa do zemalja iz kojih najvise dolaze zarazeni (Kosovo je na prvom mestu). O ovome da "mozda virus nije toliko opasan vec se samo vrsi medijska propaganda" ne bih vise da govorim, posle milion ispisanih stranica mislim da nema smisla.

Here is a brief description of the LAMP rapid test, is approved in the UK. Technology is interesting. Because small laboratories can be operated in schools and airports. Similar to PCR, fraction of the cost, fewer reagents. Up to 15,000 tests / day / device

This (small) study shows that clinical (radiographic, spirometric, blood) abnormalities are rare (well, non-existent!) in mild (no oxygen requirement) COVID-19, and infrequent in moderate disease. However.. QoL and symptom burden are massive (#LongCovid ). We need effective strategies to manage these impacts of COVID-19 - on people - perhaps rather than performing lots of testing on patients who have had mild COVID-19. Bonus: We didn't include exploratory analyses in the work, but I include a scatter plot of the correlations between some of the lung function/time from follow up / QoL. There is a hint that: QoL is worse in those with severe disease, and Symptoms and spirometry results seem to get better over time ... But numbers were a bit too small and we didn't have the time to include all the data and perform the appropriate analyses.

Radiology: Surprisingly, radiological abnormalities were rare, and most were in patients with pre-existing lung disease. 2 patients had HRCT that showed fibrosis. Importantly no patient with mild disease (no 02) had an abnormal CXR. This has useful implications for f/u! Lung function: Unsurprisingly, lung function was worse in severe disease, but actually, lung function was pretty normal in many patients in mild/moderate disease. Again, no patient with mild disease had significantly abnormal spirometry. Symptoms: Unlike radiology/lung function - symptoms were VERY common across all severities of COVID-19 - this is #LongCovid. 74% of patients had >=1 symptom at follow up. Breathlessness, insomnia, and excessive fatigue were very common. Bloods: (we looked at initial bloods in a previous paper - https://medrxiv.org/content/10.1101/2020.06.25.20137935v1). However, reassuringly, 'routine' blood abnormalities were rare in this cohort. Perhaps unnecessary in f/u? Summary: Reduced QoL and symptoms very common at around 3 months in COVID-19. However, reassuringly, CXR and lung function findings are reassuring (particularly in patients who never required oxygen). Implications? Many bodies/people have proposed f/u strategies: e.g. @BTSrespiratory (https://brit-thoracic.org.uk/about-us/covid-19-information-for-the-respiratory-community/) or this (rather excessive) figure from https://thelancet.com/journals/lanres/article/PIIS2213-2600(20)30349-0/fulltext or https://bmj.com/content/370/bm

zanima me kako su regulisali prevenciju zarazavanja aerozolima u zatvorenom (u samom hotelu).

Trebalo bi da ovim Kecmanovic ulazi u glavni zreb Sinsinatija.

https://www.spiegel.de/wissenschaft/corona-pandemie-so-unterschiedlich-meisterte-europa-die-erste-welle-a-dca7cabf-8a3b-4bbc-a776-50384285969a?sara_ecid=soci_upd_KsBF0AFjflf0DZCxpPYDCQgO1dEMph google prevod: Europe mastered the first wave so differently Six months ago the coronavirus spread rapidly in Europe. The countries reacted very differently to this - with corresponding consequences. A summary of the first wave of pandemics in numbers. When the novel coronavirus came to Europe, it happened largely undetected. People hardly knew anything about the pathogen and the symptoms of the disease. There were no precautions whatsoever. The result was an exponential growth in the number of cases. The further course is known: overcrowded emergency rooms in Italy, exit restrictions, school closings, home office. More than 200,000 people have died of Covid-19 in Europe so far. The first big wave of the pandemic varied from country to country. The analysis of the data brings some surprising insights - for example about obvious gaps in the official statistics and the specifics of Sweden in dealing with the pandemic. The focus of the evaluation is on the death statistics of the countries. Because these usually reflect the course of the pandemic more precisely than infection numbers, the level of which depends primarily on the current test strategy in the countries. 1) Where most people died 2) Covid-19 deaths not recorded 3) Where the wave first arrived 4) Where the number of cases fell again quickly 5) The countermeasures Hrvatska, Slovenija, Austrija, Italija, Irska, Francuska, Spanije imaju najvisi skor u restriktivnim merama. Belorusija i Svedska najmanje. Vidim Kosovo, BiH, ali ne vidim Srbiju. 6) Less traffic 7) At home in Europe How drastic the measures were in Italy and Spain, for example, is also shown by the presence of people in their homes. Google measured this using mobility data. The internet company constantly counts how often certain places are frequented by people, such as train stations, supermarkets or the workplace. To do this, Google uses tracking data from cell phones and compares them to average values from the past. (dijagram u originalnom clanku) Because of the strict exit restrictions, people in Madrid, for example, had to stay at home for weeks and were only allowed to go out for shopping. According to the Google data, the smallest changes were in Sweden, Finland and Germany. 8 ) Is the next wave already rolling? The first corona wave has rolled over Europe. But because the number of infections is slowly rising again in many countries, concerns about the next wave or waves are growing. At least in the death statistics - seen across Europe - no increase in the numbers has yet been discernible. (dijagram u originalnom clanku) However, the diagram also shows that around a hundred people are still dying from Covid-19 every day in Europe. Most of them in the UK, Poland, Spain and the Republic of Moldova.

Indija takodje hoce ubrzano da izbaci vakcinu, koliko vec sledece sedmice.

The time from infection with Covid-19 to the onset of symptoms is longer than originally assumed. More recent studies assume 7.5 days. This is relevant for the work of the health authorities and superspreader events. Another reason for quick tests

Harvard study shows that in comparison, Covid-19 in New York was even more fatal than the Spanish flu in 1918