Sunshine State

https://m.jpost.com/Opinion/Spread-of-COVID-19-begins-to-show-pattern-of-4-8-week-eruption-cycle-622035 Srbija se u prva dva talasa (pika, kako god) skroz uklopila u taj pattern

@Wookie For every rule, there is an exception!

Kako mislis ispada? Pa pogledaj zvonce (ignorisi one nenormalne pikove kad su brojevi prijavljeni sa zaostatkom, onih nekih 80 k):

"Most people are focused on the total number of patients, new patients and deaths worldwide. These numbers are ascending at a deadly pace, literally, and looking at the graphs gives a sense that they are climbing rapidly toward the end of the world. However, the specific data of each country, when examined separately, suggest otherwise. Although this is an early observation, it appears this disease has a periodicity of a classic Gaussian bell-curve shape wherever it appears.Ignoring both tails of the graph, it indicates that this bell's life cycle is around six to eight weeks, with its peak appearing after about two to four weeks from the time when incidents begin to occur at a substantial rate" U prevodu: Vecina ljudi usredsredjena je na ukupan broj pacijenata, novih pacijenata i smrtnih slučajeva sirom sveta. Ovi brojevi doslovno rastu smrtonosnim tempom, a gledanje grafova daje osecaj da se brzo penju prema kraju sveta. Medjutim, specificni podaci svake zemlje, kada se posebno ispitaju, sugerisu drugacije - cini se da ova bolest ima periodicnost klasičnog Gausovog oblika zvonaste krivulje gde god se pojavi. Zanemarujuci oba repa grafikona, to ukazuje na to da je zivotni ciklus ovog zvona oko sest do osam nedelja, a vrhunac se pojavljuje nakon otprilike dve do cetiri nedelje od trenutka kada se incidenti pocnu dogadjati znacajnom brzinom. I to je to - lockdown, maske, itd....sve upadne u Gausovu krivu!

"People from Pfizer have my full trust and support for new Covid-19 vaccine. For Christ's sake, those people invented Viagra!"

Osim @Kronostimekoji ima milion godina, mi ostali cemo doci na red za vakcinu negde 2036.!

Holandjani pokusavaju da ozakone nosenje maski: "People who refuse to wear a face mask in all indoor public places face a fine of €95 from December 1, sources have told the Telegraaf. At the moment, the Dutch government ‘strongly recommends’ people wear masks in shops and council buildings, but cannot make masks compulsory until new emergency legislation has been enacted in law. MPs would still have to vote on the face mask fines, which are low enough to ensure people caught without one will not end up with a criminal record. Ministers earlier lowered the fine for breaking social distancing regulations from €390 to €95 to avoid the criminal record trap."

Vrhovni vodja kaze: "Pokušaćemo do kraja januara da obezbedimo dovoljno vakcina za zdravstveni sistem, vojsku i policiju koji su najviše na udaru. Odmah za njima bili bi oni koji su već bolesni, kao i stariji. Na kraju sredovečni i mlada lica", kaže Vučić." Kako je to vojska na udaru?

Nisam videla OOO poruku! Od sad da nas blagovremeno obavestis!

Tacno se vidi da si novi ovde! @zoe Bg nas obavestava o dnevnim brojkama i to na odredjeni nacin. Pusti zenu da radi za sta je "placamo"!

Sta se desava s Madjarskom? Ako se dobro secam, oni su jos 1. septembra zabravili granice i uveli neke mere, medjutim njihovi brojevi, dva meseca kasnije, sve veci i veci?

Da se pridruzim - uglavnom kuckam sa svog tableta, ali ponekad (ako bas nije velika frka na poslu) proverim forum i s poslovnog laptopa, a tu sam konektovana preko vpn

Podseti me na onu:"Niko nije beskoristan - svako moze da posluzi, pa makar kao los primer"

Vrlo lep i prilicno razumljiv prikaz kako se razvija vakcina:

Koliko pricam s mojim kolegama po Evropi, tako je manje-vise svugde. Koleginicin muz vec par dana temperaturu preko 39 C i jos neke simptome, pitam da li je pozitivan, kaze da ne znaju, nece da ga testiraju....pitam je zasto, kaze:"That's Poland!" Jedna PM u UK prelezala 3 nedelje, ozbiljno bolesna, kaze nisu hteli da je testiraju, vec su po simptomima koje je iznela svom lekaru preko telefona zakljucili da je pozitivna i da lezi kuci, nema potrebe za testiranjem

I have to brag about this - email od direktorice naseg office-a: "Dear all, You may have noticed the amazing Pfizer announcement released earlier today. This is in direct relation to the German team, because as I write this email, there are many of our local colleagues working on this trial and, so to say, “on barricades “ for this study. It is very dynamic project, whose processes, which normally take months, are done within couple of hours. It is as exciting as it can be tiring for all who are directly involved. Yet, it is such an amazing example of what we can achieve with our work and why our work matters. I am so very proud to see our excellent team going beyond and above the norm not only for the study, but for us all regular human beings who are in desperate need of finding solution for the current covid crisis. I hope you will join me in congratulating the DACH assigned team for their achievement!!"

Da ne sirim sad i na onu ekonomsku temu, stavicu ovde - znaci, pozivamo se svi na kolektivnu odgovornost (zdravstvenu, opravdano!), ali kad topic "pare" dodju na red, nigde empatije, profit margins su najbitnije, f*ck people i njihovo prezivljavanje...ne moze se jedna godina prihvatiti da nece biti rasta od 10 %, vec samo 5% (lupam cifre) https://www.dutchnews.nl/news/2020/11/dairy-giant-frieslandcampina-to-cut-1000-jobs-in-nl-belgium-and-germany/ " Dairy giant FrieslandCampina said on Tuesday it will cut 1,000 jobs by the end of next year, blaming the direct and indirect impact of coronavirus and pressure on profit margins in the Netherlands, Belgium and Germany."

Padaju i u Holandiji, u kojoj nema takvih mera kao u Nemackoj i Francuskoj "Last Tuesday the government announced a two-week period of extra measures, including museum and amusement park closures, in an effort to give the drop in reported cases a further impulse. In mid October, when the number of new cases were nearing 10,000 a day, the government introduced what it called a ‘partial lockdown’, closing cafes and restaurants until mid December, cutting group sizes and upping hygiene regulations in shops." Nosenje maski u NL nije ozakonjeno (jos), vec samo "strongly advised"

Daj sta das!

Gore navedeni nisu ucestvovali u klinickom ispitivanju (navedeno u kojoj fazi ne), te stoga nije moguce ni oceniti safety kod takvih pacijenata. Na kraju, sve se svodi na risk/benefit - mozda ce lekar proceniti da je za onkoloskog pacijenta veci benefit da dobije vakcinu, nego sto je rizik od same vakcine

Po protokolu, exclusion criteria: Other medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study. Phases 1 and 2 only: Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV). History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s). Receipt of medications intended to prevent COVID 19. Previous clinical (based on COVID-19 symptoms/signs alone, if a SARS-CoV-2 NAAT result was not available) or microbiological (based on COVID-19 symptoms/signs and a positive SARS-CoV-2 NAAT result) diagnosis of COVID 19. Phase 1 only: Individuals at high risk for severe COVID-19, including those with any of the following risk factors: Hypertension Diabetes mellitus Chronic pulmonary disease Asthma Current vaping or smoking History of chronic smoking within the prior year BMI >30 kg/m2 Anticipating the need for immunosuppressive treatment within the next 6 months Phase 1 only: Individuals currently working in occupations with high risk of exposure to SARS-CoV-2 (eg, healthcare worker, emergency response personnel). Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination. Phase 1 only: Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention. Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection. Women who are pregnant or breastfeeding. Previous vaccination with any coronavirus vaccine. Individuals who receive treatment with immunosuppressive therapy, including cytotoxic agents or systemic corticosteroids, eg, for cancer or an autoimmune disease, or planned receipt throughout the study. Phase 1 only: Regular receipt of inhaled/nebulized corticosteroids. Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study. Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation. Previous participation in other studies involving study intervention containing lipid nanoparticles. Phase 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit. Phase 1 only: Any screening hematology and/or blood chemistry laboratory value that meets the definition of a ≥ Grade 1 abnormality. Phase 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at the screening visit. Phase 1 only: SARS-CoV-2 NAAT-positive nasal swab within 24 hours before receipt of study intervention. Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members

"With research laboratories around the world racing to develop a coronavirus vaccine, a unique challenge has emerged: how to balance intellectual property rights with serving the public good. Questions of patent protection and access to those patents has prompted an international group of scientists and lawyers to establish the Open COVID Pledge. This movement calls on organisations to freely make available their existing patents and copyrights associated with vaccine research to create an open patent pool to solve a global problem. The EU is leading the charge to create such a pool by drafting a resolution at the World Health Organisation. The US, UK and a few others have been opposed to this idea."

Pa lepo bi bilo videti neki joint effort medju pharma kompanijama da se udruze i proizvedu sto je vise moguce vakcina koje rade posao. Sigurno da Pfizer nema tolike kapacitete

Ako je kapacitet 1.3 milijardi u 2021. i da su potrebne dve doze za uspesno vakcinisanje jedne osobe, bice i dalje guravo